Drug Name

BZD (Valium) Cassette Test

Drug Uses

BZD (Valium) Cassette Test is s a rapid, visual, qualitative, competitive binding immunoassay for the detection of Benzodiazepines and Benzodiazepine metabolites in human urine.

How Taken

Allow test device, urine specimen, and/or controls to equilibrate to room temperature (15-30 degrees C) prior to testing.

• Bring the pouch to room temperature before opening it. Remove the test device from the sealed pouch and use it as soon as possible;
• Place the test device on a clean and level surface. Hold the dropper vertically and transfer 3 full drops of urine to the specimen well of the test device, and then start the timer. Avoid trapping air bubbles in the specimen well;
• Wait for the red line to appear. The result should be read at 5 minutes. Results may be stable up to 4 hours after test initiation.

Interpretation:

NEGATIVE: TWO COLOR BANDS - The appearance of two color bands within the result window indicates a negative test result. No Benzodiazepine above the cutoff level has been detected. The color of the Test band may be lighter or darker than that of the Control Band.

POSITIVE: ONE COLOR BAND - The appearance of only one color band within the result window indicates the result is positive, i.e. the specimen contains Benzodiazepine at a concentration above the cut-off level.

INVALID: Control line fails to appear. Insufficient specimen volume or incorrect procedural techniques are the most likely reasons for control line failure. Review the procedure and repeat the test using a new test device. If the problem persists, discontinue using the lot immediately and contact your local distributor.

Drug Class and Mechanism

The test provides a fast confirmation of the presence of Benzodiazepines in the subject sample at a minimum cutoff sensitivity level of 200 ng/ml BZO, the sensitivity level set by the National Institute on Drug Abuse and Departments of Health and Human Services.

Benzodiazepines can be insidious drugs of abuse because they are a frequently prescribed prescription drug. They represent a broad class of central nervous system depressants which have anxiolytic, hypnotic, anticonvulsant and muscle relaxant effects. Chronic abuse can result in addiction and retardive dyskinnesia. Benzodiazepines are used therapeutically to produce sedation, induce sleep, relieve anxiety and muscle spasms and to prevent seizures. In general, benzodiazepines act as hypnotics in high doses, as anxiolytics in moderate doses and as sedatives in low doses.

Like the barbiturates, benzodiazepines differ from one another in how fast they take effect and how long the effects last. Shorter acting benzodiazepines, used to manage insomnia, include estazolam (ProSom), flurazepam (Dalmane), quazepam (Doral), temazepam (Restoril) and triazolam (Halcyon). Benzodiazepines with longer durations of action include alprazolam (Xanax), chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), halazepam (Paxipam), lorazepam (Ativan), oxazepam (Serax) and prazepam (Centrax). Abuse of Benzodiazepines occurs primarily because of the "high" which replicates alcohol intoxication.

Missed Dose

You can use BZD (Valium) Cassette Test whenever you feel you need to do so.

Storage

BZD (Valium) Cassette Test is should be stored at room temperature (15 to 30 degrees C) for the duration of the shelf-life. BZD (Valium) Cassette Test must remain in the foil wrap or fog pouch until ready for use.

Warnings/Precautions

• BZD (Valium) Cassette Test should remain in the sealed pouch until ready for use. Once the sealed pouch has been opened.
• All urine specimens should be considered potentially hazardous and handled in the same manner as an infectious waste agent.
• BZD (Valium) Cassette Test should be discarded in a proper container after testing.
• Any positive test should be confirmed with your healthcare provider immediately.

Possible Side Effects

No possible side effects detected.

More Information

The drug test cassette format is an easy to use, simple, low cost, drug testing kit for the detection of illicit and prescription drugs. The drug test is housed in a plastic compartment that allows for the easy reading of the results. For detecting the presence of illegal drugs in the body, the cut off levels of the drug test cassette meet the standards as established by the federal government's regulatory agency (SAMHSA).